Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 

 

Peter Diamandis

Machine learning reveals genetic roots of cancers and autism

RATE THIS! +40
Posted in Software on 20th Dec, 2014 08:49 PM by AlexMuller

In the decade since the genome was sequenced in 2003, scientists, engineers and doctors have struggled to answer an all-consuming question: Which DNA mutations cause disease? A new computational technique developed at the University of Toronto may now be able to tell us.

 
A Canadian research team led by Professor Brendan Frey has developed the first method for ‘ranking’ genetic mutations based on how living cells ‘read’ DNA, revealing how likely any given alteration is to cause disease. They used their method to discover unexpected genetic determinants of autism, hereditary cancers and spinal muscular atrophy, a leading genetic cause of infant mortality.
 
Their findings appear in the December 18 issue of the leading journal Science and are already grabbing headlines. (Read the article in Quanta Magazine; read the Globe and Mail story; see coverage at autismspeaks.org.) Think of the human genome as a mysterious text, made up of three billion letters.
 
“Over the past decade, a huge amount of effort has been invested into searching for mutations in the genome that cause disease, without a rational approach to understanding why they cause disease,” said Frey. “This is because scientists didn’t have the means to understand the text of the genome and how mutations in it can change the meaning of that text.”
 
It's a puzzle that Frey points out was captured by biologist Eric Lander of the Massachusetts Institute of Technology in a famous quote: “Genome. Bought the book. Hard to read.” 

Tags: softwareAImachine learningautismgenesgeneticsgenome

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-12-21
+1
Indeed, progress in obtaining DNA sequences at low cost resulted in accumulation of huge and valuable data sets and finding the way to interpret them is hard - this is very important step forward! Reply


 

Recent headlines

  • Posted in Business on 2017-11-22 23:55:15
    How to Use Technology to Help You Become Debt-Free..read more
    Posted in Medicine on 2017-11-22 23:49:31
    Patients On Medical Cannabis More Likely To Quit Opioids,.....read more
    Posted in Business on 2017-11-22 23:45:56
    Samsung to establish an AI research hub..read more
    Posted in Medicine on 2017-11-21 09:01:15
    High Incidence of PTSD Among Cancer Patients..read more
    Posted in Science on 2017-11-21 08:56:02
    Human Memory Enhanced With a Brain Implant For the First.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a little.....read more
    Posted by AlexMuller
    Scientists detect comets outside our solar system..read more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the brain..read more
    Posted by AlexMuller
    Bacteria have a sense of touch..read more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical trial.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me