Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

When seen through the lens of technology, few resources are truly scarce; they’re mainly inaccessible. 

 

Peter Diamandis

Virus improves bone marrow transplants, kills some cancer cells

RATE THIS! +45
Posted in Science on 7th Jun, 2015 09:11 PM by AlexMuller

Researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants. For patients with blood cancers such as leukemia and multiple myeloma, a marrow transplant can be both curative and perilous.

 

It replenishes marrow lost to disease or chemotherapy but raises the risk that newly transplanted white blood cells will attack the recipient’s body. Now researchers say the myxoma virus, found in rabbits, can do double duty, quelling the unwanted side effects of a bone marrow transplant and destroying cancer cells.

 
The virus could be especially helpful to patients who have recurring cancer but cannot find a suitable bone marrow donor, said Christopher R. Cogle, M.D., the study’s lead investigator and an associate professor in the UF College of Medicine’s division of hematology and oncology. Bone marrow transplants from partially matched donors carry about an 80 percent risk of graft-versus-host disease, and the myxoma treatment would address that, Cogle said.
 
The myxoma virus also could improve bone marrow transplant options among African-Americans and the elderly. Those patients are less likely to find fully matched bone marrow donors, which raises the risk of graft-versus-host disease, according to Cogle. “Myxoma is one of the best strategies because it is effective but doesn’t affect normal stem cells,” he said.
 
During laboratory testing on human cells, the process worked this way: The myxoma virus is attached to a type of white blood cell known as a T-cell. The virus-laden white blood cells can then be delivered as part of a bone marrow transplant from a donor. That’s when the virus gets activated and goes to work.
 
It blocks graft-versus-host disease, a complication of bone marrow transplants that can cause problems including skin rash, shortness of breath, abdominal pain, jaundice and muscle weakness. In severe cases, these complications can be fatal. The white blood cells then deliver the myxoma virus to cancer cells, which are killed off by the virus.

Tags: cancerbloodvirustransplantoncologymedicinehealthresearch

Read original article » Back to category

Comments

Author: Guest
Posted: 2015-06-08
+1
Using genetically modified viruses in medical treatments has been a long standing ambition with already a few applications - this is another important step Reply


 

Recent headlines

  • Posted in Software on 2017-11-20 17:24:02
    The 3 biggest threats to your Bitcoin (and 10 tips to.....read more
    Posted in Medicine on 2017-11-20 17:20:08
    How to open the blood-brain-barrier with precision for.....read more
    Posted in Hardware on 2017-11-20 17:05:43
    China on Pace for Record Solar-Power Installations..read more
    Posted in Science on 2017-11-20 00:42:21
    Small steps forward as UN climate talks end in Bonn..read more
    Posted in Hardware on 2017-11-20 00:37:56
    US gov should support SpaceX and develop moon bases..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Martian landscapes formed from sand 'levitating' on a little.....read more
    Posted by AlexMuller
    Scientists detect comets outside our solar system..read more
    Posted by AlexMuller
    Advanced artificial limbs mapped in the brain..read more
    Posted by AlexMuller
    Bacteria have a sense of touch..read more
    Posted by AlexMuller
    Recurrent brain cancer: New hope with phase 1 clinical trial.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me