Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

Just because something doesn’t do what you planned it to do doesn’t mean it’s useless.

 

Thomas Edison

A CRISPR edit for heart disease

RATE THIS! +25
Posted in Science on 9th Mar, 2018 01:05 AM by Alex Muller

Consider this scenario: it’s 2037, and a middle-aged person can walk into a health centre to get a vaccination against cardiovascular disease. The injection targets cells in the liver, tweaking a gene that is involved in regulating cholesterol in the blood. The simple procedure trims cholesterol levels and dramatically reduces the person’s risk of a heart attack.

 

According to World Health Organization statistics published in 2015, ischaemic heart disease and stroke are the leading causes of death worldwide. About 17.7 million people died from cardiovascular disease that year, and at least three-quarters of those deaths occurred in low- and middle-income countries. Although antibody-based therapies have been launched to help those most at risk, the cost and complexity of the treatments means that a simpler, one-off fix such as a vaccine would be of benefit to many more people around the world.

 

“If you are talking about cardiovascular disease as a global health threat, which it undoubtedly is, then protecting the entire population is what we need,” says Musunuru. Lifestyle changes are important, but a substantial portion of the risk of heart failure and stroke comes from the genome. “You don’t need to choose between medicine and lifestyle. You should be doing both,” says Liu, citing people with diabetes, who fare best when they take medication and adjust their lifestyle.

 

“To vaccinate large numbers of people, that is some way off,” says Musunuru. But gene editing could reset the odds for those who didn’t win the genetic lottery, he predicts. “One way or another, genome editing is going to underlie a host of new types of cardiovascular therapies over the next 25 years.”


Tags: healthheartCRISPRgeneticsresearch

Read original article » Back to category

Comments

View comments by:


 

Recent headlines

  • Posted in Software on 2018-06-21 03:22:47
    IBM Unveils System That 'Debates' With Humans..read more
    Posted in Science on 2018-06-21 03:12:27
    NASA unveils bold new plan to protect Earth from asteroids..read more
    Posted in Science on 2018-06-21 03:03:04
    Machine learning may be a game-changer for climate.....read more
    Posted in Science on 2018-06-20 02:26:18
    Pushing the limit: could cyanobacteria terraform Mars?..read more
    Posted in Medicine on 2018-06-20 02:23:08
    Hospital Begins Testing VR As A Pain Relief Alternative..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    In five years quantum computing will be mainstream..read more
    Posted by AlexMuller
    Google partners with Johnson and Johnson to make lower cost.....read more
    Posted by AlexMuller
    Electron holography microscope with spatial resolution down to.....read more
    Posted by AlexMuller
    Lower cost advanced Nuclear power could dominate future US energy..read more
    Posted by AlexMuller
    Why Hasn’t AI Mastered Language Translation?..read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me