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Stress gene linked to heart attacks

RATE THIS! +22
Posted in Medicine on 20th Dec, 2013 12:59 AM by AlexMuller

A stress gene has been linked to having a higher risk of dying from a heart attack or heart disease.

 

Heart patients with the genetic change had a 38% increased risk of heart attack or death, say US researchers.

 
Personalised medicine may lead to better targeting of psychological or drug treatment to those most at risk, they report in PLOS ONE. The study adds to evidence stress may directly increase heart disease risk, says the British Heart Foundation.
 
A team at Duke University School of Medicine studied a single DNA letter change in the human genome, which has been linked to being more vulnerable to the effects of stress.
 
They found heart patients with the genetic change had a 38% increased risk of heart attack or death from heart disease after seven years of follow up compared with those without, even after taking into account factors like age, obesity and smoking. This suggests that stress management techniques and drug therapies could reduce deaths and disability from heart attacks, they say.
 
Dr Redford Williams, director of the Behavioural Medicine Research Center at Duke University School of Medicine, said the work is the first step towards finding genetic variants that identify people at higher risk of cardiovascular disease.
 
"This is one step towards the day when we will be able to identify people on the basis of this genotype who are at higher risk of developing heart disease in the first place," he told BBC News.

Tags: hearthealthgenesgeneticsstressDNAheart attackheart disease

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Comments

Author: Guest
Posted: 2013-12-20
+1
This is very interesting and will help to find those people that are most at risk and need most attention. This could also help to use resources where they are most needed
3 Replies
Author: Guest
Posted: 2013-12-20
+0
This is an important step in the direction of personalised medicine for cardiovascular disease. Identifying people with the genetic change could lead to early interventions for heart patients who are at high risk of dying or having a heart attack Reply
Author: Guest
Posted: 2013-12-20
+1
So far we heard a lot about personalized medicine in cancer, but in cardiovascular disease we are not nearly as far along in finding the genetic variants that identify people at higher risk. Here we have an example that will help to move toward personalized medicine in cardiovascular disease.
2 Replies
Author: Guest
Posted: 2013-12-20
+0
Yes, the good news is that knowing whether a person carries this genetic trait will help cardiovascular medicine do what cancer medicine is doing, where determining risk and arriving at treatments is becoming highly personalized. Reply
Author: Guest
Posted: 2013-12-20
+0
The most important outcome from his work is that we have a found genetic variant that can be easily identified, so we can begin to develop and test early interventions for those heart patients who are at high risk of dying or having a heart attack Reply
Reply
Reply
Author: Guest
Posted: 2013-12-20
+0
The findings raise our hopes that the discovery will lead to drugs and behavior change treatments that reduce disability and deaths from heart attack. Reply
Author: Guest
Posted: 2013-12-20
+2
It is important to managing stress level these days, as our lives get more and more harried. Some people may need pharmaceutical interventions, but for others, lifestyle methods work well, like meditation, yoga, eating well, and exercise.
1 Replies
Author: Guest
Posted: 2013-12-20
+1
There are many positive lifestyle changes that we should make to help cope with stress. A balanced diet and regular physical activity will help feel better and be able to cope with life's demands. Reply
Reply


 

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