Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

People say we're running out of energy. That's only true if we stick with these old 19th century technologies. We are awash in energy from sunlight.

 

Ray Kurzweil

 

Scientists trigger self-destruct switch in lung cancer cells

RATE THIS! +35
Posted in Medicine on 1st Nov, 2014 08:45 PM by AlexMuller

Cancer Research UK scientists have found a drug combination that can trigger the self-destruct process in lung cancer cells, paving the way for new treatments, according to research that will be presented at the National Cancer Research Institute (NCRI) Cancer Conference (link is external) in Liverpool next week.

 
When healthy cells are no longer useful they initiate a chain of events culminating in self destruction. But cancer cells swerve away from this suicide path and become immortal. This means that cells grow out of control, causing tumours to form.
 
The Cancer Research UK team, based at the UCL Cancer Institute (link is external), has successfully fixed this fault in lung cancer cells, reprogramming the cells to self-destruct. Using lung cancer cells and mice the scientists showed that the combination of two drugs, called TRAIL and a CDK9 inhibitor, altered the molecular switches in the cell suicide process, forcing the cancer cells to self-destruct.
 
Lead researcher, Cancer Research UK scientist Professor Henning Walczak from the UCL Cancer Institute, said: “Igniting the fuse that causes lung cancer cells to self destruct could pave the way to a completely new treatment approach, and leave healthy cells unharmed.

Tags: cancerlung cancercellstumorCancer Research UK

Read original article » Back to category

Comments

Author: Guest
Posted: 2014-11-02
+2
This is great! Lung cancer is in particular difficult and very little progress has been made during last 10 years to increase survival time, compared to other cancers.
1 Replies
Author: Guest
Posted: 2014-11-02
+1
Yes, there’s an urgent need to save more lives from lung cancer. These findings could one day lead to effective new treatments to help lung cancer patients and potentially those with other cancer types too Reply
Reply
Author: Guest
Posted: 2014-11-02
+2
I hope that the next step will see how this approach works in other cancer types, and could ultimately lead to testing this technique in trials to see if it can help patients-critical step
1 Replies
Author: Guest
Posted: 2014-11-02
+0
Yes, clinical trials are the key. Many findings based on cells in culture or animal models ultimately do not work for humans Reply
Reply
Author: Guest
Posted: 2016-05-06
+0
Great inhsgit! That's the answer we've been looking for. Reply


 

Recent headlines

  • Posted in Software on 2017-09-20 19:05:15
    Google boosts Cloud Natural Language API with automatic.....read more
    Posted in Software on 2017-09-20 18:55:34
    Salesforce to launch $50 million artificial intelligence.....read more
    Posted in Business on 2017-09-20 18:50:18
    The Paris agreement climate aim is 'still achievable'..read more
    Posted in Software on 2017-09-19 18:06:17
    China orders Bitcoin exchanges in capital city to close..read more
    Posted in Hardware on 2017-09-19 18:00:15
    LinkSpace is a Chinese startup that will try to make.....read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    Scientists probe Neptune's depths to reveal secrets of icy.....read more
    Posted by AlexMuller
    New terahertz imaging approach could speed up skin cancer.....read more
    Posted by AlexMuller
    Rebutting the claim that antidepressants do not work..read more
    Posted by AlexMuller
    Artificial neural networks decode brain activity during.....read more
    Posted by AlexMuller
    Four Earth-sized planets detected orbiting the nearest.....read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me