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Scientists make breakthrough in schizophrenia research

RATE THIS! +43
Posted in Medicine on 6th Jun, 2015 12:50 AM by AlexMuller

A team found that disease-linked mutations disrupt genes contributing to excitatory and inhibitory signalling, the balance of which plays a crucial role in healthy brain development and function. The breakthrough builds on two landmark studies published in the journal Nature.

 
"We're finally starting to understand what goes wrong in schizophrenia," says lead author Dr Andrew Pocklington from Cardiff University's MRC Centre for Neuropsychiatric Genetics and Genomics.
 
"Our study marks a significant step towards understanding the biology underpinning schizophrenia, which is an incredibly complex condition and has up until very recently kept scientists largely mystified as to its origins.
 
"We now have what we hope is a pretty sizeable piece of the jigsaw puzzle that will help us develop a coherent model of the disease, while helping us to rule out some of the alternatives.
 
"A reliable model of disease is urgently needed to direct future efforts in developing new treatments, which haven't really improved a great deal since the 1970s."

Tags: brainneurosciencemedicineschizophreniaresearchmental health

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Comments

Author: Guest
Posted: 2015-06-06
+1
Most mental illnesses are incredibly complex conditions and reflect complexity of the brain - getting a good model of such illnesses as is here the case for schizophrenia is a great step towards better treatment Reply


 

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