Researchers Engineer a Mightier Mouse

Mice that grow larger muscles and can run for twice as long as their unaltered littermates before tiring could point toward new treatments for the muscle loss that can occur with aging.   
 
The mice were engineered to lack a molecule called NCOR in their muscle tissue. In a second, related study, knocking out the same molecule in fat resulted in mice that were overweight but sensitive to insulin, a result that could lead to more targeted treatments for diabetes. Both studies were published in the journal Cell last week