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Cholesterol 'fuels' breast cancer

RATE THIS! +47
Posted in Medicine on 1st Dec, 2013 12:16 AM by AlexMuller

It raises the prospect that taking cholesterol-lowering drugs called statins could prevent cancer. The work, published in the journal Science, helps explain why obesity is a major risk factor for the disease. However, cancer charities cautioned that it was too soon to advise women to take statins.

 
Obesity has been linked with many cancers including those of the breast, bowel and womb. The fat in overweight people can pump out hormones, such as oestrogen, which drive the growth of cancers. A team at Duke University Medical Centre, in the US, showed that cholesterol was having a similar effect.
 
Cholesterol is broken down by the body into 27HC, which can mimic oestrogen and produce the same effect as the hormone in some tissues. Experiments on mice showed that a high fat diet increased levels of 27HC in the blood and led to tumours that were 30% larger than in mice on a normal diet.
 
Tumours were also more likely to spread. And human breast cancer tissue grew more quickly in the laboratory when it was fed 27HC.

Tags: healthcancercholesteroldiseaseobesity

Read original article » Back to category

Comments

Author: Guest
Posted: 2013-12-01
+2
Another study that links the lifestyle to cancer- this has been shown again and again and should be presented to public in a way that it gets proper attention
1 Replies
Author: Guest
Posted: 2013-12-01
+3
According WHO, about 30% of cancer deaths are due to known behavioral and dietary risks - this is alarming
5 Replies
Author: Guest
Posted: 2013-12-01
+0
Tobacco use is the most important risk factor for cancer causing about 20% of global cancer deaths and about 70% of global lung cancer deaths.
1 Replies
Author: Guest
Posted: 2013-12-01
+2
Ban on smoking is working in many countries
2 Replies
Author: Guest
Posted: 2013-12-01
+0
Yes, smoking is now not allowed in most public places – resulted in bib improvement in a short time Reply
Reply
Reply
Author: Guest
Posted: 2013-12-01
+1
The statistics from The World Health Organization should be made known to public much more readily, this could help to change peoples behavior Reply
Author: Guest
Posted: 2013-12-01
+0
Having newspaper headlines is just a beginning, there is a need for more educational programmers and efforts and new strict laws Reply
Reply
Reply
Author: Guest
Posted: 2013-12-01
+0
Breast cancer is a big problem. Breast, lung, stomach, liver and colon cancer cause the most cancer deaths each year. Reply
Author: Guest
Posted: 2013-12-01
+2
We have for some time considered that cancer is a disease of the developed world, this is not so Reply
Author: Guest
Posted: 2013-12-01
+1
Obesity has been linked to many cancer types already and this is another very good study that also makes the same point
2 Replies
Author: Guest
Posted: 2013-12-01
+0
The take home message is clear: the best ways to cut the risk of developing breast cancer are to stay a healthy weight, cut down on alcohol and keep active! Reply
Reply


 

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