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Just because something doesn’t do what you planned it to do doesn’t mean it’s useless.

 

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A Glue That Seals Heart Defects

RATE THIS! +46
Posted in Medicine on 9th Jan, 2014 01:48 AM by AlexMuller

Nearly a decade ago, Jeffrey Karp was playing around with a new, biodegradable polymer he'd made. He was a post-doctoral researcher at MIT. He ended up gluing together two pieces of glass… but later forgot about it. He ultimately developed the material for something else (as a scaffold for growing artificial organs, if you're curious).

 
"It's critical in science to be focused and to advance projects with, you know, scientific rigor, so I didn't have time to explore all of these kinds of side projects," Karp, who's now a researcher with Brigham and Women's Hospital in Boston, tells Popular Science.
 
Then he met Pedro del Nido, a cardiac surgeon at Boston Children's Hospital. Del Nido specializes in sealing up children's heart defects, literally holes in the heart that shouldn't be there. He wanted to know if Karp could make a surgical glue that would work in the heart. It was a tall order: Such a glue would have to be biodegradable, safe for use inside the body, a bit stretchy, and strong enough to hold onto a beating muscle continually awash in blood.
 
Karp remembered the cell scaffolding that could glue glass together. He started with that, and from there, he worked with del Nido and a team of surgeons and engineers to develop a glue that they recently tested in hearts of living rats and pigs. The glue is made of body-friendly chemicals that cells normally produce. In the future, del Nido hopes, this could become a gentler alternative to the stitching doctors rely on for many surgeries. "All the needles and the thread, they themselves cause injury to the healthy tissue," he says. "We've always have looked for a way to glue things together."

Tags: hearthealthcardiac surgerysurgical glue

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Comments

Author: Guest
Posted: 2014-01-09
+0
It is also interesting that they used the glue to attach a patch, made from another biodegradable material, onto the tinner wall of the still-beating hearts of four pigs Reply
Author: Guest
Posted: 2014-01-09
+2
The the new glue needs to pass further testing. If so, it will make its way into hospitals and it could be the first such glue that works under the tough conditions in the heart. Reply
Author: Guest
Posted: 2014-01-09
+2
It is interesting that researchers were inspired by spiders and insects that make secretions that stick to wet surfaces. Those secretions are viscous and water-repelling. The new glue is the same Reply
Author: Guest
Posted: 2014-01-09
+2
Another progress was a groundbreaking five-year artificial heart that had its first patient some moths ago
4 Replies
Author: Guest
Posted: 2014-01-09
+0
Depending on organ donors is a difficult situation for many patients. I hope that artificial organs with a help of 3D bio printing offer an alternative to dependence upon donation
3 Replies
Author: Guest
Posted: 2014-01-09
+0
3D printing is already known in cardiovascular innovation. Branched vessel structures can be generated by Inkjet printing technology.
 Reply
Author: Guest
Posted: 2014-01-09
+0
Recently we heard from Bioengineer that the heart is one of the easiest organs to bioprint and that they could do it in a decade Reply
Reply
Author: Guest
Posted: 2014-01-09
+0
Previous devices of this type had a relatively low autonomy. This heart will allow for more movement and less clotting. The study that is starting is being very closely watched in the medical field.... Reply
Author: Guest
Posted: 2014-01-09
+0
The new device could help thousands of people who die each year while waiting for a donor Reply
Reply


 

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