Social Media Sidebar

Announcement

Please sign up, comment on articles and bring your friends!

Current poll

PlanetTech is asking:

What do you think about our new web site?

Love it, indeed
Really good solution
Same as old one
The old one was better
This is a new option

Quote of the day

Just because something doesn’t do what you planned it to do doesn’t mean it’s useless.

 

Thomas Edison

A 3D human 'organoid' brain in a dish

RATE THIS! +44
Posted in Medicine on 14th Jun, 2015 12:08 AM by AlexMuller

Sergiu Pasca of Stanford and colleagues have developed “human cortical spheroids”, miniature cultured 3-D structures that grow and function much like the cortex of the brain of the person from whom they were derived.These “organoids” (3-D complexes of cells that function like an organ) buzz with neuronal network activity.

 
“There’s been amazing progress in this field over the past few years,” said Thomas Insel, M.D., Director of the NIH’s National Institute of Mental Health, which provided most of the funding for the study.
 
“The cortex spheroids grow to a state in which they express functional connectivity, allowing for modeling and understanding of mental illnesses. They do not even begin to approach the complexity of a whole human brain. But that is not exactly what we need to study disorders of brain circuitry.”
 
“While the technology is still maturing, there is great potential for using these assays to more accurately develop and test safety and effectiveness of new treatments before they are used in individuals with a mental illness,” said David Panchision, Ph.D., NIMH program director for stem cell research.
 
What’s next? Perhaps development of multiple neuron subtypes that normally populate the cortex, as well as long-distance connections between this cortex-like structure and other, yet to be developed, organoid structures, the researchers say.

Tags: braincellsneuroscienceresearchmedicinehealthmental health

Read original article » Back to category

Comments

Author: Guest
Posted: 2015-06-14
+1
Organoids and 3D cellular cultures could indeed be much better ways of testing effectiveness of drugs in particular when these structures are made from cells isolated from a specific patient - they could be much better option than animal models Reply


 

Recent headlines

  • Posted in Science on 2018-07-19 10:46:11
    Ground based telescopes have surpassed Hubble Space.....read more
    Posted in Science on 2018-07-19 10:41:40
    Cannabinoids may have a vast array of anti-cancer effects..read more
    Posted in Business on 2018-07-18 06:05:12
    U.S. Solar Has Grown 39-Fold In Last Decade..read more
    Posted in Business on 2018-07-18 05:58:21
    How Will We Shop in the Future?..read more
    Posted in Science on 2018-07-17 06:21:48
    How magnetized wire can detect cancer cells in your blood..read more
Posted in Business on 2013-10-10 01:33
China is working towards a manned lunar mission in about.....read more
Posted in Business on 2013-10-20 07:17
Spacex says China is their main competitor for commercial.....read more
Posted in Software on 2013-10-20 06:43
Pirate Bay Browser Clocks 1,000,000 Downloads..read more
Posted in Medicine on 2013-10-10 02:10
Google reportedly investing hundreds of millions into new.....read more
Posted in Medicine on 2013-10-14 03:13
Endothelial Cells Can Repair and Regenerate Organs,.....read more
Posted in Science on 01.01.2010
Spacex says China is their main competitor for commercial.....read more
Posted in Science on 01.01.2010
Staring at Your Phone Could Be Making You Short Sighted..read more
Posted in Science on 01.01.2010
Oculus Rift virtual reality headset coming to mobile, but.....read more
Posted in Science on 01.01.2010
China is working towards a manned lunar mission in about.....read more
Posted in Science on 01.01.2010
Delivering drugs via nanoparticles to target mitochondria..read more

Recent Blog Posts

  • Posted by AlexMuller
    In five years quantum computing will be mainstream..read more
    Posted by AlexMuller
    Google partners with Johnson and Johnson to make lower cost.....read more
    Posted by AlexMuller
    Electron holography microscope with spatial resolution down to.....read more
    Posted by AlexMuller
    Lower cost advanced Nuclear power could dominate future US energy..read more
    Posted by AlexMuller
    Why Hasn’t AI Mastered Language Translation?..read more

Login to your Account

Login to your PlanetTech Account here

Username:
Password:
Remember me
or

Create a New Account

You just need username and password

The following errors occured:
Username:
Email:
Password:
Verify password:
Remember me