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Just because something doesn’t do what you planned it to do doesn’t mean it’s useless.

 

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'Sticky balls' may stop cancer spreading

RATE THIS! +43
Posted in Medicine on 8th Jan, 2014 02:36 AM by AlexMuller

The most dangerous and deadly stage of a tumour is when it spreads around the body. Scientists at Cornell University, in the US, have designed nanoparticles that stay in the bloodstream and kill migrating cancer cells on contact.

 
They said the impact was "dramatic" but there was "a lot more work to be done". One of the biggest factors in life expectancy after being diagnosed with cancer is whether the tumour has spread to become a metastatic cancer.
 
"About 90% of cancer deaths are related to metastases," said lead researcher Prof Michael King. The team at Cornell devised a new way of tackling the problem.
 
They attached a cancer-killing protein called Trail, which has already been used in cancer trials, and other sticky proteins to tiny spheres or nanoparticles.
 
When these sticky spheres were injected into the blood, they latched on to white blood cells. Tests showed that in the rough and tumble of the bloodstream, the white blood cells would bump into any tumour cells which had broken off the main tumour and were trying to spread.
 
The report in Proceedings of the National Academy of Sciences showed the resulting contact with the Trail protein then triggered the death of the tumour cells.
 
Prof King told the BBC: "The data shows a dramatic effect: it's not a slight change in the number of cancer cells.

Tags: cancerbloodhealthmetastasistumourcellssticky balls

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Comments

Author: Guest
Posted: 2014-01-08
+2
Great news! Indeed the greatest impact of cancer on overall state for a patient is the extent of metastasis, how many and where they go. Stoping cancer spreading is an important goal
2 Replies
Author: Guest
Posted: 2014-01-08
+0
What an amazing piece of work, most excellent!
 Reply
Reply
Author: Guest
Posted: 2014-01-08
+1
I wish researchers involved loads of luck. But many promising treatments never made it beyond a petri dish and mice. Also, unless it shows truly amazing and early results with no side effects, it's 10 years minimum away from final approval.
3 Replies
Author: Guest
Posted: 2014-01-08
+0
So far the evidence suggests the system has no knock-on effect for the immune system and does not damage other blood cells or the lining of blood vessels. Good start Reply
Reply
Author: Guest
Posted: 2014-01-08
+2
Researchers are proposing to use nanoparticles before surgery or radiotherapy, which can result in tumour cells being shed from the main tumour. Good application Reply
Author: Guest
Posted: 2014-01-08
+0
Surgery and radiation are effective at treating primary tumors, but metastatic cancer cells are difficult to find and treatment of the spreading cancer problematic- now we could have these promising nanoparticles to help here Reply
Author: Guest
Posted: 2014-01-08
+0
We should think about cancer prevention, not just cures. Many studies linkthe lifestyle to cancer- this has been shown again and again and should be presented to public in a way that it gets proper attention
3 Replies
Author: Guest
Posted: 2014-01-08
+0
According WHO, about 30% of cancer deaths are due to known behavioral and dietary risks - this is alarming
3 Replies
Author: Guest
Posted: 2014-01-08
+0
These should be headlines in all main newspapers worldwide Reply
Author: Guest
Posted: 2014-01-08
+0
It is quite amazing that about 30% of cancers can be avoided by changing our habits and lifestyle Reply
Reply
Author: Guest
Posted: 2014-01-08
+0
Tobacco use is the most important risk factor for cancer causing about 20% of global cancer deaths and about 70% of global lung cancer deaths. Reply
Reply
Author: Guest
Posted: 2014-01-08
+0


 

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